Long-term effectiveness - 40%
Short-term effectiveness - 60%
Safety - 50%
Price - 70%
Should you buy it?
I think there are far better brain supplements out there than Natrogix PrimeMind. Basic bacopa extract and an over-reliance on caffeine. Never good. I’d use a different nootropic.
TL;DR – Summary
Natrogix PrimeMind looks like a very exciting supplement at first glance. The branding is great and it’s already getting a lot of attention online. But sadly the formula just doesn’t back up the promises made by the manufacturer. Low quality extracts, low doses, and some useless ingredients combine to make a disappointing nootropic. PrimeMind’s effects will overwhelmingly come from the caffeine and the Ginkgo biloba. You’re better off just using those substances individually.
Natrogix PrimeMind Review
PrimeMind is a brand new natural nootropic supplement. It is made by a company called Natrogix. I’ve never heard of these guys before now. It looks like they’ve only just started out, but PrimeMind is not their only product. They already have a wide range of products on offer, including coconut oil, krill oil, multivitamins, a probiotic, and of course, PrimeMind nootropic.
PrimeMind brain supplement is not currently listed on the Natrogix official website. But it is listed on Amazon. According to that page, PrimeMind delivers the following core benefits:
- Increased focus and concentration
- Improved memory function
- Greater mental energy levels
- Improved mood
You can see exactly what Natrogix promises by looking at the banner ads that accompany the PrimeMind Amazon page:
I think it’s very ambitious to promise that your product can “slow down or even reverse certain effects that ageing has on the brain”.
Natrogix aren’t explicitly claiming to be able to reverse age-related cognitive decline. They’ve been very careful not to. But they are insinuating that PrimeMind can do that.
I think this is always intentionally misleading. You can delay or slow down age-related cognitive decline through supplementation. But as far as we know, you can’t reverse it.
So, does Natrogix PrimeMind really work? What does it actually do? Is PrimeMind safe? What kind of side effects can you expect?
Read my full Natrogix PrimeMind review below and find out! Have you used this product yourself? Share your experiences in the comments section at the end.
Natrogix PrimeMind ingredients
The manufacturer can make all the fantastical claims they want – if I don’t see good ingredients and proper doses to back it up, then I’ll pass.
Here is the Natrogix PrimeMind ingredients list as shown on the label:
Here is a list of the ingredients so it’s a bit clearer:
- 300mg Coryceps mushrooms
- 300mg Bacopa monnieri
- 100mg Ginkgo biloba
- 100mg Glucuronolactone
- 100mg DiCaffeine Malate (73% caffeine)
- 25mg Phosphatidylserine (25% purity)
- 50mg DMAE
Here is a quick overview of what the key ingredients are, what they do, and how they work!
Cordyceps mushroom is not a very common ingredient in nootropic supplements today; only a handful of stacks are using it. There’s a lot of hype surrounding cordyceps at the moment, but I believe it’s over-hyped. I’ve not seen any studies showing a convincing, substantial improvement in cognitive function resulting from cordyceps supplementation.
Bacopa monnieri is an immensely powerful memory enhancer. It doesn’t have an immediate impact; instead, it gradually improves memory retention, recall, and accuracy over time. Supplementing with this stuff for many weeks and months can have a profound impact on your memory. Bacopa has been extensively tested and has been found to be extremely effective across populations. We get 300mg in Natrogix PrimeMind, but there is a problem with the extract (more on this below).
A classic nootropic – this one has been a staple feature of brain supplements for years, and it will be for years to come. Ginkgo biloba causes the blood vessels in your brain to expand, allowing more oxygen and nutrients to reach your brain cells. The end result is overall improved cognition. Ginkgo is especially useful if you think you may have poor cerebral circulation.
This is often found in energy drinks. However, it seems to be included in energy drinks for no reason whatsoever. There isn’t a single study out there which shows that glucuronolactone independently increases mental energy, focus, stamina, or any aspect of mental performance for that matter. This is more of a gimmick than a nootropic in my book.
Obviously, this is just a compound of caffeine and malic acid. I really don’t know why Natrogix have used this rather than straight caffeine. There is nothing about this compound that improves the action of caffeine – caffeine is powerful enough as it is! If anything, we just have useless malic acid taking up valuable formula space which could have gone to more caffeine!
Phosphatidylserine is a phospholipid used by the brain to construct new cell membranes. To put it simply, you need phosphatidylserine to make new brain cells, and to get rid of old ones that have reached the end of their life cycle (it is involved in apoptosis signalling). You can get enough from food. However, I’m not interested in enough; I want to optimize. You should too. If you do, supplementation is the way forward.
DMAE is a cholinergic compound. It is a choline analogue which crosses the blood-brain barrier and confers extra choline to the brain. Once there, this choline is used to make more acetylcholine. This increases all-round cognitive performance. The only problem is that DMAE is my least favorite cholinergic. In my opinion, it is the least efficient way to raise acetylcholine levels. It is also unreliable and relatively side effect-prone. Not ideal in a premium nootropic like PrimeMind.
My thoughts on the PrimeMind formula
I’m really disappointed with the PrimeMind formula. I see a couple of good things here, but I see far more problems.
First of all, I notice that Natrogix haven’t given us an extract potency for the Bacopa monnieri extract.
I don’t know what percentage of this extract is bacosides. These are the active compounds in Bacopa monnieri – the stuff that actually improves memory function. Everything else is just useless plant material.
The lack of an extract percentage on the label is a very big problem for me – why would you hide this if it was a potent extract? Most manufacturers brag about it. I therefore think it’s likely that the extract quality is very low.
Then there’s the use of largely unproven, over-hyped ingredients.
The worst offender here is Glucuronolactone. I often see this listed on the ingredients list for energy drinks. Many people assume that because it is prevalent in energy drinks, then it must increase energy levels, mental stimulation, and so on. Well, I’m yet to see a shred of evidence for this. Some studies have found that glucuronolactone is probably not effective for increasing energy levels at all. Others have noted the lack of human studies, and the large doses that are found in supplements (source).
In my opinion, Cordyceps mushrooms don’t actually improve cognitive performance all that much. More research is needed of course, but I don’t think they deserve all the hype they’re getting right now. I’m yet to see an independent trial in which cordyceps had a substantial, meaningful effect on cognitive function. There are some promising studies – I’m not doubting that. But I just need more proof before I’m convinced.
Finally, there is the fact that Natrogix PrimeMind uses substandard ingredients (despite much more effective alternatives being readily available).
For example, each serving of Natrogix PrimeMind contains 50mg of DMAE.
DMAE is a poor cholinergic. It is significantly less powerful than Citicoline and Alpha-GPC. It does not share the same additional benefits that people derive from Alpha-GPC and Citicoline, such as improved cell membrane formation. Worse still, DMAE is extremely unreliable – many users fail to get any benefits out of it whatsoever. A small but significant number of users report serious side effects; something which I can’t say about Citicoline.
It’s also a shame to see that Natrogix have tried to be clever, opting for DiCaffeine Malate instead of straight caffeine. The malic acid does not make the caffeine any more effective than regular, pure caffeine anhydrous. I believe that this compound has been used because it looks ‘jazzy’ on the ingredients list. At 73% caffeine by weight, all the malic acid has done is displace potentially useful caffeine.
All things considered, I can’t say that I’m terribly impressed with the PrimeMind formula!
I think this is a poorly put together brain supplement. The caffeine will increase focus, motivation, and energy levels in a very short space of time. The Ginkgo biloba will certainly improve cognitive performance. It will also support good brain health and functionality going forward.
But aside from these two effects, I don’t think many users are going to get much out of PrimeMind.
Price – How much is Natrogix PrimeMind?
Natrogix PrimeMind is sold for $14.99 on Amazon at the time of writing.
That is actually very reasonable for a 30 days supply.
On a day-to-day basis, that is a far lower cost than most natural nootropic supplements. It is definitely a lot cheaper than any of the stacks on my list of recommended brain supplements.
However, that should really tell you something important!
I don’t think it’s always about the price tag – value for money and how much something costs are two very different things.
While PrimeMind is much cheaper than many other nootropics, it provides substantially less value and far milder results.
So you really need to decide what you want – a lower price, or real results!
Is PimeMind safe? Will it cause side effects?
In my opinion, caffeine is a great nootropic when used sparingly, as and when it is needed. It is not a suitable ingredient in a daily, long-term brain supplement. You probably get all the caffeine you need from tea and coffee; there’s no reason why you should be taking more caffeine from supplements every single day.
Now, the caffeine dose in PrimeMind is quite small. It’s only 73mg (73% of the DiCaffeine Malate). That’s about what you’ll get from a standard Americano.
But taking that extra shot of espresso every single day, for many weeks and months, can really add up!
It’s also more than enough to cause mild side effects in some users, including:
- Rapid breathing
- Rapid heart rate
- Difficulty focusing
You really need to work out how much caffeine you’re already consuming before you start adding in any more from supplements. Take caffeine seriously; it’s one powerful stimulant.
I’m not a doctor. This is in no way supposed to be medical advice. I know nothing about your present circumstances; your medications, pre-existing conditions, allergies – nothing. All I can do is highlight the most obvious, general dangers for the average hypothetical user. I’m drawing on my own research and experience to do this, nothing more. You must do your own research and talk to a doctor before using nootropics.
Final verdict – Should you use Natrogix PrimeMind?
In my honest opinion, Natrogix PrimeMind is not the supplement it makes itself out to be.
It presents itself as a new, cutting-edge premium brain supplement. In reality, it is just a combination of the same old, tired ingredients I’ve seen dozens of times before. The only difference is that PrimeMind contains some ingredients that aren’t normally used in nootropics…because they don’t improve cognitive performance!
Even though the price tag is $15, I honestly think PrimeMind is over-priced.
Considering the Bacopa monnieri extratc could be 1% bacosides for all we know, I consider this a simple caffeine and Ginkgo biloba stack. The other ingredients are dosed too low – or they’re too unreliable – to have much of an impact.
You can buy Ginkgo biloba and caffeine separately for not very much money at all.
Doing so means you can skip the potentially harmful and unpredictable DMAE and Glucuronolactone.
If you’re looking for a pre-made nootropic stack that takes care of every aspect of cognitive function, check out my list of recommended nootropics.
PrimeMind doesn’t meet my standards. I don’t think it’s good enough for you either – not when there are so many alternatives offering better results and fewer side effect risks.
To learn more about how nootropics work, check out my big list of ingredients.